Select publications:

Spontaneous cSCC Murine Model Shows Limited Response to PD-1 Blockade and Radiation Combination Therapy
Hosseini TM, Ho L, Pham TB, Molinolo A, Jones R, Vera D, Sharabi A, Park SJ, Guo T. Cancers (Basel). 2025 Dec 31;18(1):146.

Aberrant Splicing Burden Predicts Immune Infiltration and Prognosis in Head and Neck Squamous Cell Carcinomas
Kalavacherla S, Bendik J, Victor M, Carter H, Califano JA, Guo T. Head Neck. 2026 Jan;48(1):45-55.

Indisulam Shows an Anti-Cancer Effect on HPV+ and HPV- Head and Neck Cancer
Hosseini, T.M.; Jang, S.S.; Bendik, J.; Guo, T. Cancers (Basel) 2025, 17, doi:10.3390/cancers17071072.

Identifying Strong Neoantigen MHC-I/II Binding Candidates for Targeted Immunotherapy with SINE
Bendik, J.; Castro, A.; Califano, J.; Carter, H.; Guo, T. Int J Mol Sci 2024, 26, doi:10.3390/ijms26010205.
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The Mutational and Microenvironmental Landscape of Cutaneous Squamous Cell Carcinoma: A Review
Hosseini, T.M.; Park, S.J.; Guo, T. Cancers (Basel) 2024, 16, doi:10.3390/cancers16162904.
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OutSplice: A Novel Tool for the Identification of Tumor-Specific Alternative Splicing Events
Bendik, J.; Kalavacherla, S.; Webster, N.; Califano, J.; Fertig, E.J.; Ochs, M.F.; Carter, H.; Guo, T.W. BioMedInformatics 2023, 3, 853-868, doi:https://doi.org/10.3390/biomedinformatics3040053

Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma
Guo, T.; Zambo, K.D.A.; Zamuner, F.T.; Ou, T.; Hopkins, C.; Kelley, D.Z.; Wulf, H.A.; Winkler, E.; Erbe, R.; Danilova, L.; et al.
Epigenetics 2020, 15, 959-971, doi:10.1080/15592294.2020.1741757

A novel splice variant of LOXL2 promotes progression of human papillomavirus-negative head and neck squamous cell carcinoma
Liu, C.; Guo, T.; Sakai, A.; Ren, S.; Fukusumi, T.; Ando, M.; Sadat, S.; Saito, Y.; Califano, J.A.
Cancer 2020, 126, 737-748, doi:10.1002/cncr.32610.

Characterization of Alternative Splicing Events in HPV-Negative Head and Neck Squamous Cell Carcinoma Identifies an Oncogenic DOCK5 Variant
Liu, C.; Guo, T.; Xu, G.; Sakai, A.; Ren, S.; Fukusumi, T.; Ando, M.; Sadat, S.; Saito, Y.; Khan, Z.; et al.
Clin Cancer Res 2018, 24, 5123-5132, doi:10.1158/1078-0432.CCR-18-0752

Splice Expression Variation Analysis (SEVA) for inter-tumor heterogeneity of gene isoform usage in cancer
Afsari, B.; Guo, T.; Considine, M.; Florea, L.; Kagohara, L.T.; Stein-O'Brien, G.L.; Kelley, D.; Flam, E.; Zambo, K.D.; Ha, P.K.; et al.
Bioinformatics 2018, 34, 1859-1867, doi:10.1093/bioinformatics/bty004

A Novel Functional Splice Variant of AKT3 Defined by Analysis of Alternative Splice Expression in HPV-Positive Oropharyngeal Cancers 
Guo, T.; Sakai, A.; Afsari, B.; Considine, M.; Danilova, L.; Favorov, A.V.; Yegnasubramanian, S.; Kelley, D.Z.; Flam, E.; Ha, P.K.; et al.
Cancer Res 2017, 77, 5248-5258, doi:10.1158/0008-5472.CAN-16-3106

Characterization of functionally active gene fusions in human papillomavirus related oropharyngeal squamous cell carcinoma
Guo, T.; Gaykalova, D.A.; Considine, M.; Wheelan, S.; Pallavajjala, A.; Bishop, J.A.; Westra, W.H.; Ideker, T.; Koch, W.M.; Khan, Z.; et al. 
Int J Cancer 2016, 139, 373-382, doi:10.1002/ijc.30081